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As both play very important roles in the immune response, and the status or availability of one has been shown to directly affect the other, it is likely that deficiency of either can have a direct effect on the severity of COVID-19 as well as many other diseases therefore, taking steps to ensure adequate levels of both is essential to better health

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Ibuprofen was shown to attenuate the metabolism of AEA by FAAH in rat brain 71

N Engl J Med 345(12):861869 Moorhead JF, Brunton C, Varghese Z (1997) Glomerular atherosclerosis

Methionine in the form of S-adenosylmethionine (SAM) is required for many methylation reactions, including DNA methylation